Transcription factor II H
A COMPLEX THAT IS CAPABLE OF KINASE ACTIVITY DIRECTED TOWARDS THE C-TERMINAL DOMAIN (CTD) OF THE LARGEST SUBUNIT OF RNA POLYMERASE II AND IS ESSENTIAL FOR INITIATION AT RNA POLYMERASE II PROMOTERS IN VITRO. IT IS COMPOSED OF THE CORE TFIIH COMPLEX A
TFIIH; Transcription Factor II H
Transcription factor II Human (transcription factor II H; TFIIH) is an important protein complex, having roles in transcription of various protein-coding genes and DNA nucleotide excision repair (NER) pathways. TFIIH first came to light in 1989 when general transcription factor-δ or basic transcription factor 2 was characterized as an indispensable transcription factor in vitro.